Dr Jonathon Hull

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About me

Module leader for the FdSc module Pathophysiology of Disease.

Module leader for the MSc module Practical Skills.

Programme champion for the Healthcare Science programme.

A Fellow of the Higher Education Academy, PGCert (UWE, Bristol).

Completed PhD and p​ostdoc examining the expression of the human branched chain aminotransferase protein and the metaboism of the branched chain amino acids in the human brain in both health and disease (UWE).​

Area of expertise

TEACHING

In teaching I cover a range of subjects at varying levels. Subjects like Genetics, Pathophysiology and Biochemistry I cover from level 1 (in Cell Biochemistry and Genetics and Pathophysiology of Diseaase) to level 3 and MSc level (in Medical Genetics and Clinical Biochemsitry).

Every year I take final year undergraduate students and masters students for their projects. These will involve techniques such as cell culture, flow cytommetry and wet transfer Western blot. 

RESEARCH

Over the course of my research career, I have gained a working understanding of molecular biology, protein biochemistry, neuroanatomy and neuropathology, particularly associated with dementia and cancer pathology.  I have collaborated with key researchers in neurological disease such as Professor Seth Love and Professor Patrick Kehoe at the South West Dementia Brain Bank (University of Bristol); Dr.  Kathreena Kurian at the Department of Neuropathology (Southmead Hospital); and Dr. Mehta at the Department of Haematology (University Hospital, Bristol).

KEY PUBLICATIONS

Hull, J., El Hindy, M., Kehoe, P., Chalmers, K., Love, S., Conway, M.  (2015) Regional increase in the expression of the BCAT proteins in Alzheimer's disease brain:  Implications in glutamate toxicity.  Journal of Alzheimer's disease; 45 (3):  891-905. 

Hull, J., Patel, V.B., Hutson, S.M., Conway, M.E.  (2015) New insights into the role of the branched chain aminotransferase proteins in the human brain.  Journal of Neuroscience Research; 93(7):  987-998. 

​Hull, J., El Hindy, M., Kehoe, P., Chalmers, K., Love, S., Conway, M.  (2012) Distribution of the branched chain aminotransferase proteins in the human brain and their role in glutamate regulation.  Journal of Neurochemistry; 123 (6):  997-1009. 

Publications

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